NIH HEAL Initiative Budget

Fiscal Years 2019-2022 Budget*

HEAL funds 42 distinct research programs, which are led by most NIH Institutes, Centers, and Offices.

Translation of Research to Practice for the Treatment of Opioid Addiction

• HEALing Communities Study | 343.7M
• Enhancing NIDA Clinical Trial Network to Address Opioids | 190.3M
• Justice and Community Opioid Innovation Network (JCOIN) | 128.2M
• Behavioral Research to Improve MAT (BRIM) | 38.4M
• Recovery Research Networks | 13.8M
• Harm Reduction Approaches to Reduce Overdose Death | 19.7M
• Improving Delivery of Healthcare Services for Polysubstance Use | 16M
• The Continuum of Care in Hospitalized Patients with Opioid Use Disorder and Infectious Complications of Drug Use (CHOICE) | 2.3M

New Strategies to Prevent and Treat Opioid Addiction

• Optimizing Care for People with OUD and Mental Health Conditions | 63.8M
• Preventing Opioid Use Disorder (Prevention) | 65.5M
• Sleep Dysfunction as a Core Feature of Opioid Use Disorder and Recovery | 25.6M
• Optimizing the Duration, Retention, and Discontinuation of Medication Treatment for Opioid Use Disorder - CTN | 48.2M
• Prevention of Progression to Moderate or Severe Opioid Use Disorder (STOP) Subsyndromal | 12.5M
• Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care) | 3.4M
• Monthly Injectable Buprenorphine for Methamphetamine Use Disorder (MURB) | 2.5M

Enhanced Outcomes for Infants and Children Exposed to Opioids

• Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) | 69.4M
• HEALthy Brain and Child Development Study (HBCD) | 38.3M Phase II

Novel Therapeutic Options for Opioid Use Disorder and Overdose

• Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose | 420M
• Development of Novel Immunotherapies for Opioid Addiction | 41.4M

Clinical Research in Pain Management

• Back Pain Consortium Research Program (BACPAC) | 134.7M
• Pain Management Effectiveness Research Network (ERN) | 90.9M
• Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) | 40.4M
• Early Phase Pain Investigation Clinical Network (EPPIC-Net) | 52.3M
• Integrated Approach to Pain and Opioid Use in Hemodialysis Patients (HOPE) | 28.4M
• Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR) | 20.6M
• Advancing Health Equity in Pain Management | 15.4M
• Discovery and Validation of Biomarkers, Endpoints and Signatures for Pain Conditions | 46.3M

Preclinical and Translational Research in Pain Management

• Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain | 90.3M
• Preclinical Screening Platform for Pain (PSPP) | 43.4M
• Translational Research to Advance Testing of Novel Drugs and Human Cell-Based Screening Platforms to Threat Pain and Opioid Use Disorder | 119.2M
• Translating Discoveries to Devices for Effective Pain Treatment | 51.5M
• Development and Optimization of Non-Addictive Therapies to Treat Pain | 55.3M
• Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN) | 31.1M

Cross-Cutting Research

• Increasing Participant Diversity, Inclusion and Engagement in HEAL | 14.8M
• Training the Next Generation of Researchers in HEAL | 18.1M
• Leveraging Existing and Real-Time Opioid and Pain Management Data | 53.1M
• Translating Data 2 Action to Prevent Overdose | 12.1M
• Stigma in Pain Management and Opioid Use Disorder | 1.6M
• Small Business Programs | 93.4M

*The Acute to Chronic Pain Signatures and Stimulating Peripheral Activity to Relieve Conditions (SPARC) programs are supported by the NIH Common Fund and do not appear on this page.