Fiscal Year 2019 Budget for the NIH HEAL Initiative*

Focused Medications Development to Treat Opioid Use Disorder and Prevent/Reverse Overdose

Institute(s): NIDA

2019 Budget: $140.74 million

Development of Novel Immunotherapeutics for Opioid Addiction

Institute(s): NIAID

2019 Budget: $9.96 million

Safety and Efficacy of ANS-6637 to Reduce Drug Craving and Harm (SEARCH) in People with Opioid Use Disorder in Highly Affected Urban Populations

Institute(s): NIAID

2019 Budget: $2.20 million

Advancing Clinical Trials for Neonatal Opioid Withdrawal (ACT-NOW)

Institute(s): NICHD

2019 Budget: $24.40 million

National Drug Abuse Treatment Clinical Trials Network Enhancement

Institute(s): NIDA

2019 Budget: $72.88 million

Multi-Site Demonstration Implementation Research Study/HEALing Communities Study

Institute(s): NIDA

2019 Budget: $115.50 million

Justice & Community Opioid Intervention Network

Institute(s): NIDA

2019 Budget: $58.00 million

Behavioral Interventions for Prevention of Opioid Use Disorder or Adjunct to Medication Assisted Treatment-SAMHSA Opioid State Targeted Response Grants

Institute(s): NCCIH

2019 Budget: $3.89 million

Development of Novel Drugs and Human Cell-Based Screening Platforms to Treat Pain and Opioid Use Disorder

Institute(s): NCATS

2019 Budget: $44.54 million

Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment

Institute(s): NINDS

2019 Budget: $38.03 million

Engineering a Preclinical Testing Platform to Identify and Profile Non-Addictive Therapeutics for Pain

Institute(s): NINDS

2019 Budget: $9.08 million


Biomarkers, Endpoints, and Signatures for Pain Conditions

Institute(s): NINDS

2019 Budget: $19.54 million


Public-Private Partnership: Early Phase Pain Investigation Network (EPPIC-Net)

Institute(s): NINDS

2019 Budget: $27.32 million

Optimizing Collaborative Care for Patients with Opioid Use Disorders and Common Mental Disorders

Institute(s): NIMH

2019 Budget: $50.00 million

Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM)

Institute(s): NCCIH, NIAMS

2019 Budget: $9.90 million

Determining the Optimal Length of Buprenorphine Treatment

Institute(s): NIDA

2019 Budget: $9.00 million

Preventing At-Risk Adolescents from Developing Opioid Use Disorder as They Transition into Adulthood

Institute(s): NIDA, NIAAA

2019 Budget: $20.69 million

Sleep Dysfunction as a Core Feature of Opioid Use Disorder and a Potential Target for Facilitating Recovery

Institute(s): NHLBI

2019 Budget: $24.98 million

Management of Sub-Syndromal and Low-Severity Opioid Use Disorder

Institute(s): NIDA, NIMH

2019 Budget: $3.15 million

Integrated Approach to Pain and Opioid Use in Hemodialysis Patients

Institute(s): NIDDK

2019 Budget: $27.40 million

Translating Discoveries into Effective Devices for Pain Treatment

Institute(s): NINDS, NIBIB, OD

2019 Budget: $15.61 million

Behavioral Research to Improve Medication-Based Treatment Outcomes

Institute(s): NCCIH

2019 Budget: $13.16 million

HEALthy Brain and Child Development Study


2019 Budget: $7.86 million

NIH HEAL Initiative Pain Management Effectiveness Research Network

Institute(s): NCATS, NINDS

2019 Budget: $29.64 million

Back Pain Research Consortium

Institute(s): NIAMS

2019 Budget: $113.61 million


TOTAL: $890.82 million

* The Acute to Chronic Pain Signatures and Stimulating Peripheral Activity to Relieve Conditions (SPARC) programs are supported by the NIH Common Fund and do not appear on this page.