Overview

Through the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, NIH supports research to enhance pain management and improve treatment for opioid misuse and addiction. The NIH HEAL Initiative includes research focus areas led by 12 NIH Institutes and Centers supporting hundreds of projects that reflect the full spectrum of research from basic science to implementation research.

Funded Projects

2021
Advancing the science on recovery community centers to support persons treated with medications for opioid use disorder
Nov 11, 2021
2021
Building a Lasting Foundation to Advance Actionable Research on Recovery Support Services for High Risk Individuals with Opioid Use Disorder: The Initiative for Justice and Emerging Adult Populations
Nov 11, 2021
2021
Studies to Advance Recovery Supports (STARS) in Central Appalachia
Nov 11, 2021
2021
Delivering Transcutaneous Auricular Neurostimulation as an Adjunct Treatment for Neonatal Opioid Withdrawal Syndrome
Oct 12, 2021
2020
TRIALS COORDINATING CENTER TO REDUCE SUBSTANCE USE, HIV RISK BEHAVIORS, & CRIME
Mar 19, 2020

Open Funding Opportunities

2020
HEAL Initiative: Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) (UG3/UH3, Clinical Trials Optional)
Jan 23, 2020
2021
HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management (R61/R33, Clinical Trial Required)
Nov 16, 2021
2021
HEAL initiative: Pharmacotherapies to Reverse Opioid Overdose Induced Respiratory Depression Without Central Opioid Withdrawal (Target Validation and Candidate Therapeutic Development) (UG3/UH3 Clinical Trials Not Allowed)
Sep 30, 2021
2021
Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management [SUBMISSION AND EXPIRATION DATE ARE ESTIMATED]
Jul 20, 2021
2019
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
Oct 03, 2019

Closed Funding Opportunities

2019
HEAL Initiative: Request for Administrative Supplements to Existing Grants to Accelerate Research on Preventing Opioid Use Disorder in Older Adolescents and Young Adults (ages 16-30)
Sep 25, 2019
2019
Behavioral & Integrative Treatment Development Program (R01 Clinical Trial Optional)
Sep 25, 2019
2019
The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Optional)
Sep 25, 2019
2019
Development of a Device to Objectively Measure Pain (R43/R44)
Sep 25, 2019
2021
Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Sickle Cell Disease Pain Management Trials Utilizing the Pain Effectiveness Research Network Cooperative Agreement (UG3/UH3, Clinical Trial Required) [DATES ARE ESTIMATED]
Oct 15, 2021