Overview

Through the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, NIH supports research to enhance pain management and improve treatment for opioid misuse and addiction. The NIH HEAL Initiative includes research focus areas led by most NIH Institutes and Centers supporting hundreds of projects that reflect the full spectrum of research from basic science to implementation research.

Funded Projects

2022
Total-Body PET for Assessing Myofascial Pain
Oct 01, 2022
2022
Phase 1 and 2 Studies of Sublingual Dexmedetomidine, an Alpha 2 Adrenergic Agonist, for Treating Opioid Withdrawal
Oct 01, 2022
2022
The Effects of Hydrocodone Rescheduling on Pain Management of Older Lung Cancer Patients
Oct 01, 2022
2022
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
Oct 01, 2022
2022
Fibromyalgia TENS in Physical Therapy Study (TIPS): An Embedded Pragmatic Clinical Trial
Oct 01, 2022

Open Funding Opportunities

2023
HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)
Jan 03, 2023
2022
HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (K99/R00 Independent Clinical Trial Not Allowed)
Dec 15, 2022
2022
HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)
Dec 15, 2022
2022
HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required)
Dec 15, 2022
2022
HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Basic Experimental Studies with Humans Required)
Dec 15, 2022

Closed Funding Opportunities

2020
HEAL Initiative: Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) (UG3/UH3, Clinical Trials Optional)
Jan 23, 2020
2021
HEAL Initiative: HEAL Data2Action Modeling and Economic Resource Center (U24 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: Pilot & Feasibility Trials to Improve Prevention and Treatment Service Delivery for Polysubstance Use (R34-Clinical Trial Optional)
Dec 29, 2021