Overview

Through the Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, NIH supports research to enhance pain management and improve treatment for opioid misuse and addiction. The NIH HEAL Initiative includes research focus areas led by 12 NIH Institutes and Centers supporting hundreds of projects that reflect the full spectrum of research from basic science to implementation research.

Funded Projects

2019
1-Year Sustained Release Naltrexone Implant for the prevention of relapse to opioid dependence
Sep 25, 2019
2019
1/2 Optimizing access, engagement and assessment to elucidate prenatal influences on neurodevelopment: The Brains Begin Before Birth (B4) Midwest Consortium
Sep 25, 2019
2019
1/3 Promoting Resilience in Children: Protocol Development for a Birth Cohort Study To Assess Factors Impacting Neurodevelopment
Sep 25, 2019
2019
1/4 Investigation of opioid exposure and neurodevelopment (iOPEN)
Sep 25, 2019
2019
Wearable nanocomposite sensor system for diagnosing mechanical sources of low back pain and guiding rehabilitation
Nov 19, 2019

Open Funding Opportunities

2019
Notice of Information: Clinical Trials that Explore Non-Addictive Therapeutics for Pain Conditions under the Early Phase Pain Investigation Clinical Network (EPPIC-Net)
Sep 25, 2019
2019
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
Sep 25, 2019
2019
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R21 Clinical Trial Not Allowed)
Sep 25, 2019
2019
HEAL/NINDS Early Phase Pain Investigation Clinical Network (EPPIC-Net): Opening to applications for non-addictive pain therapeutics
Sep 11, 2019
2019
HEAL Initiative: America’s Startups and Small Businesses Build Technologies to Stop the Opioid Crisis (R43/R44 - Clinical Trial Optional)
Sep 25, 2019

Closed Funding Opportunities

2019
Translational Research on Interventions for Adolescents in the Legal System: TRIALS (U01)
Sep 25, 2019
2019
The National Drug Abuse Treatment Clinical Trials Network (UG1)
Sep 25, 2019
2019
PHS 2016-02 Omnibus Solicitation of the NIH, CDC, FDA, and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
Sep 25, 2019
2019
Behavioral Interventions for Prevention of Opioid Use Disorder or Adjunct to Medication Assisted Treatment-SAMHSA Opioid STR Grants (R21/R33)
Sep 25, 2019
2019
HEAL Initiative: America’s Startups and Small Businesses Build Technologies to Stop the Opioid Crisis (R41/R42 - Clinical Trial Optional)
Sep 25, 2019