Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
3R01DA056675-01S1
Domain-specific inhibition of angiotensin-converting enzyme as a therapeutic strategy for opioid use disorders Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF MINNESOTA ROTHWELL, PATRICK (contact); MORE, SWATI S Minneapolis, MN 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-23-189
1R43DA060033-01A1
Xylazine and opioid overdose mitigation therapy using decoy receptor biomimetic nanoparticles, NarcoBond platform Cross-Cutting Research Small Business Programs NIDA CIBOTS, INC. ESMAELI-AZAD, BABAK San Diego, CA 2024
NOFO Title: PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
NOFO Number: PA-23-230
1R21DA060711-01
A National Survey on Naloxone Use and Access New Strategies to Prevent and Treat Opioid Addiction NIDA RAND CORPORATION POWELL, DAVID Pittsburgh, PA 2024
NOFO Title: Mechanism for Time-Sensitive Drug Abuse Research (R21 Clinical Trial Optional)
NOFO Number: PAR-22-027
1U01DA059791-01A1
PF614-MPAR: clinical development of opioid with oral overdose protection Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA ENSYSCE BIOSCIENCES, INC. KIRKPATRICK, LYNN La Jolla, CA 2024
NOFO Title: Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
NOFO Number: PAR-22-202
1K23DA060310-01
Behavior Change Components to Enhance Opioid Disposal After Surgery Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF UTAH HUANG, LYEN CAMILLE Salt Lake City, UT 2024
NOFO Title: HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K23 - Clinical Trial Required)
NOFO Number: PAS-22-207
4UH3DA048338-03
A Long-Acting Bioabsorbable Naltrexone Subcutaneous Implant for Opioid Use Disorder Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA DRUG DELIVERY COMPANY, LLC COHEN, STEVEN M (contact); BENNER, JEFFREY Salisbury, MD 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
1R01DA062152-01
Disparities in early childhood health outcomes following prenatal opioid exposure and protective health system factors: a population perspective Enhanced Outcomes for Infants and Children Exposed to Opioids NIDA DARTMOUTH HITCHCOCK CLINIC LEYENAAR, JOANNA Lebanon, NH 2024
NOFO Title: Accelerating the Pace of Drug Abuse Research Using Existing Data (R01 Clinical Trial Optional)
NOFO Number: RFA-DA-22-037
1R61DA059035-01A1
Together Against Overdose: community developed technology to encourage drug checking, distribution of harm reduction supplies, and linkage to services Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA NDRI-USA, INC. ARONSON, IAN DAVID New York, NY 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R61DA062321-01
Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management (SUPPORT-MOM) Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA WASHINGTON UNIVERSITY IN ST. LOUIS KELLY, JEANNIE CHEN (contact); BAUMANN WALKER, ANA St. Louis, MO 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
4R33DA059169-02
Leveraging Data to Action: Accelerating Emergency Department OUD Care by Improving Data Access and Infrastructure Cross-Cutting Research HEAL Data2Action (HD2A) NIDA YALE UNIVERSITY VENKATESH, ARJUN KRISHNA (contact); HAWK, KATHRYN; TAYLOR, RICHARD ANDREW New Haven, CT 2024
NOFO Title: HEAL Initiative: HEAL Data2Action Innovation and Acceleration Projects, Phased Awards (R61/R33, Clinical Trial Optional)
NOFO Number: RFA-DA-23-057
1R01DA061773-01
Neurotensin receptor 1 as a novel target for opioid use disorder and discovery of new small molecule probes Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA UNIVERSITY OF MINNESOTA SLOSKY, LAUREN M (contact); OLSON, STEVEN H Minneapolis, MN 2024
NOFO Title: HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R01 Clinical Trial Not Allowed)
NOFO Number: RFA-DA-24-063
1R34DA062280-01
Adapting and Testing a Youth Overdose Prevention Toolkit New Strategies to Prevent and Treat Opioid Addiction NIDA UNIVERSITY OF BRITISH COLUMBIA FAST, DANYA (contact); HADLAND, SCOTT EVAN Vancouver, BC 2024
NOFO Title: Adolescent Overdose Prevention and SUD Treatment Initiative (R34 - Clinical Trial Optional)
NOFO Number: RFA-DA-25-031
4U01HL150835-02
Evaluating the Role of the Orexin System in Circadian Rhythms of Sleep and Stress in Persons on Medication-Assisted Treatments for Opioid Use Disorder New Strategies to Prevent and Treat Opioid Addiction Sleep Dysfunction as a Core Feature of Opioid Use Disorder and Recovery NHLBI JOHNS HOPKINS UNIVERSITY HUHN, ANDREW S (contact); FINAN, PATRICK Baltimore, MD 2024
NOFO Title: HEAL Initiative: Sleep and Circadian-Dependent Mechanisms Contributing to Opiate Use Disorder (OUD) and Response to Medication Assisted Treatment (MAT) (U01 Clinical Trial Optional)
NOFO Number: RFA-HL-19-029
1R90DA062893-01
University of Utah Program to Provide Pain Research Knowledge (UP3RK) Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF UTAH FRITZ, JULIE M Salt Lake City, UT 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
3OT2OD037907-01S1
Southeast Enrollment Center Consortium 2 (SEEC-2) New Strategies to Prevent and Treat Opioid Addiction OD UNIVERSITY OF MIAMI SCHOOL OF MEDICINE ZUCHNER, STEPHAN (contact); MCCAULEY, JACOB L Coral Gables, FL 2024
NOFO Title: All of Us Engagement, Communications, and Enrollment Partnerships
NOFO Number: OTA-22-006
1OT2DA061133-01
Understanding Pain Expression in Wabanaki People during Recovery: Enhancing Wabanaki Research, Data Self-Determination, and Capacity Development Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA WABANAKI HEALTH AND WELLNESS CAMMACK, RALPH Bangor, ME 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061134-01
Promoting Community Wellbeing Through Indigenous Science and Healing Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA WASHINGTON STATE UNIVERSITY MCDONELL, MICHAEL G (contact); ECHO-HAWK, ABIGAIL; RASMUS, STACY M; VENNER, KAMILLA L Pullman, WA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1R01DA059457-01A1
A Growing Crisis of Novel Injection-Related Wounds and Skin & Soft Tissue Infections among People Who Inject Drugs: A Community-Based, Longitudinal Investigation in North Carolina New Strategies to Prevent and Treat Opioid Addiction NIDA RESEARCH TRIANGLE INSTITUTE ZIBBELL, JON ERIC Research Triangle Park, NC 2024
NOFO Title: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
NOFO Number: PA-20-185
3R01DA057613-01S1
Assessing the Reach, Effectiveness, and Implementation of Multiple Harm Reduction Interventions. Translation of Research to Practice for the Treatment of Opioid Addiction Harm Reduction Research Network NIDA RESEARCH TRIANGLE INSTITUTE KRAL, ALEXANDER H Research Triangle Park, NC 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3UG1DA013732-25S2
CTN - Effects of semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro and Zepbound) on incidence and outcomes of stimulant use disorders and opioid use disorder in real-world populations: target tr Translation of Research to Practice for the Treatment of Opioid Addiction Enhancing the National Drug Abuse Treatment Clinical Trials Network to Address Opioids NIDA UNIVERSITY OF CINCINNATI WINHUSEN, T JOHN Cincinnati, OH 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3U24DA055325-04S2
The Healthy Brain and Child Development National Consortium Administrative Core Enhanced Outcomes for Infants and Children Exposed to Opioids HEALthy Brain and Child Development (HBCD) Study NIDA UNIVERSITY OF CALIFORNIA SAN DIEGO CHAMBERS, CHRISTINA (contact); NELSON, CHARLES ALEXANDER La Jolla, CA 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3R33DA057747-04S1
The influence of neighborhood factors and social determinants of health on OUD treatment outcomes Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF MARYLAND MAGIDSON, JESSICA F College Park, MD 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-23-189
1R43DA060717-01
Integration of an opioid dispensing, monitoring, and disposal platform with a hospital pharmacy to reduce opioid use by discharged emergency department patients Cross-Cutting Research Small Business Programs NIDA ADDINEX TECHNOLOGIES, INC. ROSLYAKOV, STANISLAV New York, NY 2024
NOFO Title: PHS 2023-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
NOFO Number: PA-23-231
1UG3DA060053-01
Development of a Safer and More Effective Ibogaine Analog for the Treatment of Opioid Use Disorder Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA GILGAMESH PHARMACEUTICALS, INC. MAREK, GERARD JOSEPH New York, NY 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
NOFO Number: PAR-22-200
1R61DA060426-01
Evaluating Vending Machines providing Naloxone to Prevent Overdose in American Indian Communities New Strategies to Prevent and Treat Opioid Addiction NIDA UNIVERSITY OF CALIFORNIA SAN DIEGO GAINES, TOMMI LYNN (contact); KNOX, AMY La Jolla, CA 2024
NOFO Title: Time-Sensitive Opportunities for Health Research (R61/R33 Clinical Trial Not Allowed)
NOFO Number: PAR-22-233