The Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, is a trans-NIH research effort focused on improving prevention and treatment for opioid misuse and addiction and enhancing pain management.

The NIH HEAL Initiative is organized into six research focus areas. Within those focus areas, most NIH Institutes and Centers are leading more than 30 research programs to find scientific solutions to the opioid crisis.

View the NIH HEAL Initiative research plan and HEAL-Supported Research Publications.