There are multiple effective evidence-based treatments and programs for opioid use disorder (OUD). Most Americans at risk for or with OUD, however, do not receive appropriate treatment for their disorder. At the same time, opioid overdoses continue to kill thousands of Americans. To better understand how promising and evidence-based strategies and treatments might help more people with OUD, the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, will deploy a suite of implementation science efforts to test the integration of evidence-based interventions in an array of settings.

Research Programs

The HEALing Communities Study will test the integration of prevention, overdose treatment, and medication-based treatment in select communities hard hit by the opioid crisis. This comprehensive treatment model will be tested in a coordinated array of settings, including primary care, emergency departments, and other community settings. Findings will establish best practices for integrating prevention and treatment strategies that can be replicated by communities nationwide.

The NIH HEAL Initiative will expand the size and scope of research conducted by the National Drug Abuse Treatment Clinical Trials Network (CTN). This expansion will help address emergent needs presented by the opioid crisis. The CTN will integrate new opioid-related research questions into studies currently underway, expedite new studies in general medical and other settings, and enhance clinical and research training opportunities.

The Justice Community Opioid Intervention Network (JCOIN) will study quality care for opioid misuse and OUD in justice populations. JCOIN will help create partnerships between local and state justice systems and community-based treatment providers. Findings will address the critical need to improve the quality of OUD treatment in the justice system.

The NIH HEAL Initiative will work with the Substance Abuse and Mental Health Services Administration to learn if combining behavioral interventions with medication-based treatment for OUD can lead to better results. Some of the behavioral interventions to be studied include mindfulness meditation, cognitive behavioral therapy, and multidisciplinary rehabilitation. Researchers will examine whether these behavioral interventions improve adherence to medication-based treatment, improve outcomes, and reduce relapse. 

Through the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative® and the National Institute on Drug Abuse, NIH supports the Recovery Research Networks. This program focuses on developing multi-stakeholder networks (researchers, payors, providers, people in recovery) to support the development of infrastructure to advance the science of long-term recovery. Five projects form the Consortium on Addiction Recovery Science (CoARS). Collectively, these projects are developing resources to support recovery research with a focus on community-based recovery centers, justice-involved youth, family-based recovery, recovery in rural settings, and integrated networks of care.

Funded Projects

2021
Advancing the science on recovery community centers to support persons treated with medications for opioid use disorder
Nov 11, 2021
2021
Building a Lasting Foundation to Advance Actionable Research on Recovery Support Services for High Risk Individuals with Opioid Use Disorder: The Initiative for Justice and Emerging Adult Populations
Nov 11, 2021
2021
Studies to Advance Recovery Supports (STARS) in Central Appalachia
Nov 11, 2021
2021
Adapting the HOPE Online Support Intervention to Increase MAT Uptake Among OUD Patients
Oct 12, 2021
2021
Exploring Health Beliefs for Community Engagement and Diversity in Clinical Trials
Oct 12, 2021

Open Funding Opportunities

2021
HEAL Initiative: HEAL Data2Action Modeling and Economic Resource Center (U24 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)
Dec 30, 2021
2021
HEAL Initiative: Research Networks for the Study of Recovery Support Services for Persons Treated with Medications for Opioid Use Disorder (R24 Clinical Trial Optional)
Dec 29, 2021
2021
HEAL Initiative: Pilot & Feasibility Trials to Improve Prevention and Treatment Service Delivery for Polysubstance Use (R34-Clinical Trial Optional)
Dec 29, 2021

Closed Funding Opportunities

2019
The National Drug Abuse Treatment Clinical Trials Network (UG1)
Sep 25, 2019
2019
HEALing Communities Study: Developing and Testing an Integrated Approach to Address the Opioid Crisis (Data Coordinating Center) (UM1- Clinical Trials Not Allowed)
Sep 25, 2019
2019
The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Optional)
Sep 25, 2019
2019
HEAL Initiative: Justice Community Opioid Innovation Network (JCOIN) Methodology and Advanced Analytics Resource Center (U2C Clinical Trial Not Allowed)
Sep 25, 2019
2019
Translational Research on Interventions for Adolescents in the Legal System: TRIALS (U01)
Sep 25, 2019

NIH establishes network to improve opioid addiction treatment in criminal justice settings

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NIH. National Institutes of Health

NIH establishes network to improve opioid addiction treatment in criminal justice settings

The National Institutes of Health will award 12 grants to form the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD) in criminal justice settings nationwide.

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Logo of the Joe Piscopo Show, featuring an image of Joe Piscopo

Dr. Baker on the HEALing Communities Study

Director of the HEAL Initiative Dr. Rebecca Baker discusses the HEALing Communities Study on AM 970's The Joe Piscopo Show.

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