Director, Washington University Pain Center, Washington University School of Medicine
Robert Gereau, Ph.D., is a researcher interested in determining the cellular and molecular changes that underlie the development of chronic pain conditions. His research employs a combination of behavioral studies, patch clamp electrophysiology, optogenetics, in vivo imaging, molecular and genetic approaches to understand the signaling pathways involved in nervous system plasticity that underlies the development of chronic pain. The mission of the lab is to identify novel approaches to reverse this maladaptive plasticity to provide new therapeutic strategies to reduce pain and its impact on patient quality of life. Work in the lab also includes clinical science aimed at translating findings from the lab into new or improved therapies for patients with pain. These studies include comparative studies of human physiology to preclinical models, as well as healthy human volunteer studies aimed at establishing proof of concept for novel analgesic therapies based on findings from the laboratory.