Overview

Through the Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, NIH supports research to enhance pain management and improve treatment for opioid misuse and addiction. The NIH HEAL Initiative includes research focus areas led by 12 NIH Institutes and Centers supporting hundreds of projects that reflect the full spectrum of research from basic science to implementation research.

Funded Projects

2020
Automation and validation of human on a chip systems for drug discovery
Mar 19, 2020
2020
Development of a fixed-dose combination therapy for the treatment of chronic musculoskeletal pain
Mar 19, 2020
2020
Discovery of T-type Calcium Channel Antagonists from Multicomponent Reactions and Their Application in Paclitaxel-induced Peripheral Neuropathy
Mar 19, 2020
2020
Using Virtual Reality Psychological Therapy to Develop a Non-Opioid Chronic Pain Therapy
Mar 19, 2020
2020
University of Michigan BACPAC Mechanistic Research Center
Mar 19, 2020

Open Funding Opportunities

2019
HEAL Initiative: EPPIC-Net Pain Research Asset Application (OT1)
Sep 03, 2019
2019
Analytical and/or Clinical Validation of a Candidate Biomarker for Pain (R61/R33 Clinical Trial Optional)
Sep 25, 2019
2019
Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain (R61/R33 Clinical Trial Optional)
Sep 25, 2019
2020
HEAL Initiative: Back Pain Consortium (BACPAC) Research Program Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions
Jan 15, 2020
2019
HEAL Initiative: America’s Startups and Small Businesses Build Technologies to Stop the Opioid Crisis (R43/R44 - Clinical Trial Optional)
Sep 25, 2019

Closed Funding Opportunities

2019
Translational Research on Interventions for Adolescents in the Legal System: TRIALS (U01)
Sep 25, 2019
2019
The National Drug Abuse Treatment Clinical Trials Network (UG1)
Sep 25, 2019
2019
PHS 2016-02 Omnibus Solicitation of the NIH, CDC, FDA, and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
Sep 25, 2019
2019
Behavioral Interventions for Prevention of Opioid Use Disorder or Adjunct to Medication Assisted Treatment-SAMHSA Opioid STR Grants (R21/R33)
Sep 25, 2019
2019
HEAL Initiative: America’s Startups and Small Businesses Build Technologies to Stop the Opioid Crisis (R41/R42 - Clinical Trial Optional)
Sep 25, 2019