Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
1OT2DA061113-01
Absentee Shawnee Tribal Health System: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program- Addressing Overdose, Substance Use, Mental Health, and Pain (OT2) Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA ABSENTEE SHAWNEE TRIBE OF OKLAHOMA PATERNITE, HADYN KERNAL (contact); NAEL, SIAVASH Shawnee, OK 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
4UH3DA048338-03
A Long-Acting Bioabsorbable Naltrexone Subcutaneous Implant for Opioid Use Disorder Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA DRUG DELIVERY COMPANY, LLC COHEN, STEVEN M (contact); BENNER, JEFFREY Salisbury, MD 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
4UH3DA048767-03
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid Analgesics Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA EICOSIS, LLC CORTES-PUCH, IRENE (contact); HAMMOCK, BRUCE D Davis, CA 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
1R61DA062217-01
A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk New Strategies to Prevent and Treat Opioid Addiction NIDA BOSTON MEDICAL CENTER BAGLEY, SARAH M (contact); YULE, AMY Boston, MA 2024
NOFO Title: Phased Research to Support Substance Use Epidemiology, Prevention, and Services Studies (R61/R33 Clinical Trials Optional)
NOFO Number: PAR-24-062
1R61DA060426-01
Evaluating Vending Machines providing Naloxone to Prevent Overdose in American Indian Communities New Strategies to Prevent and Treat Opioid Addiction NIDA UNIVERSITY OF CALIFORNIA SAN DIEGO GAINES, TOMMI LYNN (contact); KNOX, AMY La Jolla, CA 2024
NOFO Title: Time-Sensitive Opportunities for Health Research (R61/R33 Clinical Trial Not Allowed)
NOFO Number: PAR-22-233
1U01DA060704-01A1
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdose Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER FRANCE, CHARLES P San Antonio, TX 2024
NOFO Title: Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
NOFO Number: PAR-22-202
1U01DA059791-01A1
PF614-MPAR: clinical development of opioid with oral overdose protection Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA ENSYSCE BIOSCIENCES, INC. KIRKPATRICK, LYNN La Jolla, CA 2024
NOFO Title: Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
NOFO Number: PAR-22-202
1UG3DA061620-01
Registration Development Program for LUCEMYRA (Lofexidine) Label Expansion for Opioid Withdrawal Treatment in Adolescents Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA USWM, LLC MASSEY, VERONICA LYNCH (contact); SCHMIDT, LEE Louisville, KY 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
NOFO Number: PAR-22-200
1UG3DA059278-01A1
Development of SBS-226, a MOR agonist / DOR antagonist, for OUD Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA SPARIAN BIOSCIENCES, INC. REICH, JEFFREY New York, NY 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
NOFO Number: PAR-22-200
1UG3DA060053-01
Development of a Safer and More Effective Ibogaine Analog for the Treatment of Opioid Use Disorder Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA GILGAMESH PHARMACEUTICALS, INC. MAREK, GERARD JOSEPH New York, NY 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
NOFO Number: PAR-22-200
1R21DA061660-01
Simulating the Impact of Office-Based Methadone Prescribing and Pharmacy Dispensing on OUD Treatment and Overdose in New York State: An Agent-Based Modeling Approach Cross-Cutting Research NIDA NEW YORK UNIVERSITY SCHOOL OF MEDICINE KRAWCZYK, NOA (contact); JORDAN, ASHLY ELIZABETH New York, NY 2024
NOFO Title: Mechanism for Time-Sensitive Drug Abuse Research (R21 Clinical Trial Optional)
NOFO Number: PAR-22-027
4UH3DA054825-03
A novel and highly selective orexin 1 receptor antagonist for the treatment of patients with opioid use disorder. Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA ASTRAZENECA PHARMACEUTICALS, LP GURRELL, IAN Wilmington, DE 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trial Optional)
NOFO Number: PAR-20-092
1R44DA061722-01
NX90: A Treatment for Overdose Caused by High Potency Opioids Cross-Cutting Research Small Business Programs NIDA SERODOPA THERAPEUTICS, INC. VORONKOV, MICHAEL V Gainesville, FL 2024
NOFO Title: PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
NOFO Number: PA-23-230
1R43DA060033-01A1
Xylazine and opioid overdose mitigation therapy using decoy receptor biomimetic nanoparticles, NarcoBond platform Cross-Cutting Research Small Business Programs NIDA CIBOTS, INC. ESMAELI-AZAD, BABAK San Diego, CA 2024
NOFO Title: PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
NOFO Number: PA-23-230
1R34DA059770-01
Addressing racial disparities in opioid overdose deaths using an open source peer recovery coach training and multimodal mobile health platform New Strategies to Prevent and Treat Opioid Addiction NIDA FRIENDS RESEARCH INSTITUTE, INC. TOFIGHI, BABAK (contact); LEKAS, HELEN-MARIA; LEWIS, CRYSTAL FULLER Baltimore, MD 2024
NOFO Title: Pilot and Feasibility Studies in Preparation for Substance Use Prevention Trials (R34 Clinical Trial Optional)
NOFO Number: PA-21-110
3R01DA057668-01S1
Enhancing Precision in Overdose Mortality Prediction through Data Linkage: A Heterogeneous Capture-Recapture Approach to Estimating Opioid Use Disorder Prevalence in Ohio Cross-Cutting Research Leveraging Existing and Real-Time Opioid and Pain Management Data NIDA OHIO STATE UNIVERSITY FERNANDEZ, SOLEDAD A (contact); FAREED, NALEEF Columbus, OH 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
1OT2DA061064-01
Partnering to Achieve Wellness for Native Americans through Indigenous Knowledge (PAWNIK) Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA RAND CORPORATION D'AMICO, ELIZABETH J (contact); JOHNSON, CARRIE Pittsburgh, PA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1OT2DA061111-01
AASTEC-AAIHB N CREW Program Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA ALBUQUERQUE AREA INDIAN HEALTH BOARD ENGLISH, KEVIN CHARLES (contact); POOLA, CHARLENE Albuquerque, NM 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061140-01
Building iCRISP: Indigenous Community-Informed Research Infrastructure to address Substance Misuse and Pain Management Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA LUMBEE LAND DEVELOPMENT, INC. BEASLEY, CHERRY M (contact); BELL, RONNY A; IRBY, MEGAN; PENZIEN, DONALD BAIRD Pembroke, NC 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061138-01
Commitment to Recovery: Alaska Native Community Needs for Substance Use Treatment Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA SOUTHCENTRAL FOUNDATION SHANE, ALIASSA (contact); MICHLIG, GEORGIA J; TRINIDAD, SUSAN BROWN Anchorage, AK 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061133-01
Understanding Pain Expression in Wabanaki People during Recovery: Enhancing Wabanaki Research, Data Self-Determination, and Capacity Development Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA WABANAKI HEALTH AND WELLNESS CAMMACK, RALPH Bangor, ME 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061112-01
Heal(th) From Within: A Research Collaborative to Share our Journeys to Wellness Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA ALASKA NATIVE TRIBAL HEALTH CONSORTIUM FORD, TARA (contact); JESSEN, CORNELIA M Anchorage, AK 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061065-01
Promoting Wellness among Native Americans in Urban Areas Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA MONTANA CONSORTIUM FOR URBAN INDIAN HEALTH GREEN, BRANDN Helena, MT 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA060972-01
Yakama Nation: Native Collective Research Effort to Enhance Wellness Program Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA CONFEDERATED TRIBES AND BANDS OF THE YAKAMA NATION SALUSKIN, KATHERINE R (contact); GEORGE, NACHYA Toppenish, WA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061143-01
Indigenous Strengths as Solutions in a Public Health Crisis (Project ISH) Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA NORTHWEST INDIAN COLLEGE ALEXANDER, CHARENE (contact); JUAREZ, BARBARA A Bellingham, WA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007