Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
1OT2DA061065-01
Promoting Wellness among Native Americans in Urban Areas Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA MONTANA CONSORTIUM FOR URBAN INDIAN HEALTH GREEN, BRANDN Helena, MT 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061144-01
Development and Implementation of a Community-Led Research Program in the Utah Navajo Health System Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA UTAH NAVAJO HEALTH SYSTEM, INC. HENDY, RICK (contact); KELLEY, ALAN TAYLOR Montezuma Creek, UT 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061064-01
Partnering to Achieve Wellness for Native Americans through Indigenous Knowledge (PAWNIK) Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA RAND CORPORATION D'AMICO, ELIZABETH J (contact); JOHNSON, CARRIE Pittsburgh, PA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1UG3DA059278-01A1
Development of SBS-226, a MOR agonist / DOR antagonist, for OUD Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA SPARIAN BIOSCIENCES, INC. REICH, JEFFREY New York, NY 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
NOFO Number: PAR-22-200
4UH3DA050325-03
Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and Man Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA PENN STATE HEALTH HERSHEY MEDICAL CENTER GRIGSON, PATRICIA SUE (contact); BRICK, TIMOTHY R; BUNCE, SCOTT C; NYLAND, JENNIFER E Hershey, PA 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
1R61DA061335-01
Development and Evaluation of a Mobile Health Intervention for Co-Morbid Opioid Use Disorder and Posttraumatic Stress Disorder During Community Re-entry Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA UNIVERSITY OF RHODE ISLAND WEISS, NICOLE HOLLAND Kingston, RI 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R61DA062351-01
A Bundled Intervention to End Opioid Overdoses by Increasing Treatment Uptake Post Emergency Department Discharge Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA UNIVERSITY OF ALABAMA AT BIRMINGHAM LI, LI Birmingham, AL 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R01DA061771-01
Pharmacological targeting of nascent modulators of opioid signaling Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA UNIVERSITY OF FLORIDA MARTEMYANOV, KIRILL A Gainesville, FL 2024
NOFO Title: HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R01 Clinical Trial Not Allowed)
NOFO Number: RFA-DA-24-063
1R34DA062260-01
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD adherence to adolescents with OUD New Strategies to Prevent and Treat Opioid Addiction NIDA MARYLAND TREATMENT CENTERS, INC. WENZEL, KEVIN R (contact); FISHMAN, MARC Baltimore, MD 2024
NOFO Title: Adolescent Overdose Prevention and SUD Treatment Initiative (R34 - Clinical Trial Optional)
NOFO Number: RFA-DA-25-031
1OT2DA061112-01
Heal(th) From Within: A Research Collaborative to Share our Journeys to Wellness Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA ALASKA NATIVE TRIBAL HEALTH CONSORTIUM FORD, TARA (contact); JESSEN, CORNELIA M Anchorage, AK 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061063-01
GATHER: Growing a Tribal Healing Effort through Research Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA UNIVERSITY OF WASHINGTON PARKER, MYRA ELIZABETH (contact); MAGARATI, RATNA MAYA Seattle, WA 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1R43DA060033-01A1
Xylazine and opioid overdose mitigation therapy using decoy receptor biomimetic nanoparticles, NarcoBond platform Cross-Cutting Research Small Business Programs NIDA CIBOTS, INC. ESMAELI-AZAD, BABAK San Diego, CA 2024
NOFO Title: PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
NOFO Number: PA-23-230
1U01DA060704-01A1
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdose Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER FRANCE, CHARLES P San Antonio, TX 2024
NOFO Title: Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
NOFO Number: PAR-22-202
4R33DA057660-02
Fatal Overdose Review Teams - Research to Enhance Surveillance Systems (FORTRESS) Cross-Cutting Research Translating Data 2 Action to Prevent Overdose NIDA INDIANA UNIVERSITY INDIANAPOLIS AALSMA, MATTHEW (contact); RAY, BRADLEY; REDA, KHAIRI Indianapolis, IN 2024
NOFO Title: HEAL Initiative: HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-22-051
1R61DA061377-01
Impact of collaborative care for pregnant persons with opioid use disorder in low-resource obstetric settings Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION KRANS, ELIZABETH E (contact); JARLENSKI, MARIAN PATRICIA Pittsburgh, PA 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R33DA061260-01
Efficacy and implementation considerations for a peer-led motivational interviewing intervention to promote uptake of drug checking services and safer drug use behaviors to reduce overdose Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA UNIVERSITY OF CALIFORNIA SAN DIEGO STRATHDEE, STEFFANIE A (contact); BORQUEZ, ANNICK La Jolla, CA 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-054
1R21DA062022-01
Neuropeptide S Receptor 1 as a Novel Target for Reducing Opioid Self-Administration and Opioid Relapse Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER TUNSTALL, BRENDAN Memphis, TN 2024
NOFO Title: HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-DA-24-064
1OT2DA061140-01
Building iCRISP: Indigenous Community-Informed Research Infrastructure to address Substance Misuse and Pain Management Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA LUMBEE LAND DEVELOPMENT, INC. BEASLEY, CHERRY M (contact); BELL, RONNY A; IRBY, MEGAN; PENZIEN, DONALD BAIRD Pembroke, NC 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA062969-01
Hawaii N CREW Research Resource Center Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA UNIVERSITY OF HAWAII AT MANOA GOEBERT, DEBORAH A (contact); ONOYE, JANE Honolulu, HI 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1R21DA061660-01
Simulating the Impact of Office-Based Methadone Prescribing and Pharmacy Dispensing on OUD Treatment and Overdose in New York State: An Agent-Based Modeling Approach Cross-Cutting Research NIDA NEW YORK UNIVERSITY SCHOOL OF MEDICINE KRAWCZYK, NOA (contact); JORDAN, ASHLY ELIZABETH New York, NY 2024
NOFO Title: Mechanism for Time-Sensitive Drug Abuse Research (R21 Clinical Trial Optional)
NOFO Number: PAR-22-027
4UH3DA048767-03
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid Analgesics Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA EICOSIS, LLC CORTES-PUCH, IRENE (contact); HAMMOCK, BRUCE D Davis, CA 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
1R61DA059035-01A1
Together Against Overdose: community developed technology to encourage drug checking, distribution of harm reduction supplies, and linkage to services Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA NDRI-USA, INC. ARONSON, IAN DAVID New York, NY 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R61DA062321-01
Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management (SUPPORT-MOM) Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA WASHINGTON UNIVERSITY IN ST. LOUIS KELLY, JEANNIE CHEN (contact); BAUMANN WALKER, ANA St. Louis, MO 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R61DA061831-01
Engaging People Who Use Drugs in Harm Reduction Service Delivery: An Intravention to Reduce Risk of HIV, HCV, Overdose, and Injection-related Infections in Rural Appalachia New Strategies to Prevent and Treat Opioid Addiction NIDA UNIVERSITY OF KENTUCKY YOUNG, APRIL MARIE Lexington, KY 2024
NOFO Title: Rural Community-Centered Drug Misuse Prevention and Harm Reduction Research: Addressing Implementation, Dissemination, and Equity Challenges across the Continuum of Care (R61/R33 Clinical Trial Only)
NOFO Number: RFA-DA-24-036
1R21DA062256-01
The Youth Empowerment Study (YES) New Strategies to Prevent and Treat Opioid Addiction NIDA BOSTON MEDICAL CENTER BAGLEY, SARAH M (contact); GREEN, TRACI C Boston, MA 2024
NOFO Title: Adolescent Overdose Prevention and SUD Treatment Initiative (R21 - Clinical Trial Not Allowed)
NOFO Number: RFA-DA-25-030