3R01NR015642-04S1

https://projectreporter.nih.gov/project_info_details.cfm?aid=9755187&icde=41497968

Awarded

2018

218499

Enhance pain management

Wound care procedures (WCPs), such as dressing changes, cause moderate to severe pain in 74% of patients, nearly half of whom experience severe pain. Mainstay recommendations to prevent pain during WCPs have focused on either administration of preventive and procedural analgesia or use of expensive, non-adherent dressings. However, it is unclear which patients to target for analgesia or expensive dressings, leading to their inappropriate over- or underuse. To achieve the aims of the study, a comprehensive set of wound, patient, and biological factors will be measured concurrently with pain during a dressing change among a sample of 450 inpatients with open wounds. A predictive model will be developed and biological mechanisms will be examined using logistic regression. The proposed study has the potential to make significant contributions because clinicians will be able to target those patients requiring preventive pain control, thereby eliminating the spiraling impact of painful procedures on nociceptor sensitization.

NINR

GARDNER, SUE E

University of Iowa

Iowa City, IA

RFA-NR-15-001

https://grants.nih.gov/grants/guide/rfa-files/RFA-NR-15-001.html

Chronic Wounds: Advancing the Science from Prevention to Healing (R01)

Thu, 03/19/2020 - 12:00pm

Research Project Grants

Iowa

On