Find HEAL-Funded Clinical Studies for Pain

Clinical studies rely on the generosity of patients who participate in research to improve human health. 

• Learn more about NIH clinical studies.
• Check to see if you are eligible to participate in a HEAL clinical study testing various pain management approaches. Select the study title to view its entry on ClinicalTrials.gov. 

A Collaborative Intervention for Improving Cancer Pain Management in Rural and Hispanic Cancer Survivors (ASCENT) (Arizona, Florida, Minnesota, Wisconsin)

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain (SKOAP) (Alabama, Arkansas, California, Colorado, Florida, Georgia, Illinois, Iowa, Maryland, Massachusetts, Minnesota, New York, North Carolina, Ohio, Oregon, Tennessee, Utah, Virginia, Washington)

An Internet-based Program to Help Cancer Survivors Manage Pain (IMPACTS) (Arkansas, California, Colorado, Georgia, Hawaii, Illinois, Iowa, Kentucky, Louisiana, Michigan, Minnesota, Missouri, New Jersey, North Carolina, Ohio, South Carolina, Virginia, Wisconsin)

Cancer Pain Management Using a Web-based Intervention (CAI) (Texas)

Divided or Single Exposure (DOSE) Study (Maryland)

EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA (EN21-01) (California, Florida, Illinois, Massachusetts, New York, Pennsylvania, Virginia, Washington, Wisconsin)

Equity Using Interventions for Pain and Depression (EQUIPD) (Indiana)

Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial (Illinois, Iowa, South Dakota, Wisconsin)

Group-based Integrative Pain Management in Primary Care Safety Net Clinics (IPMP+) (California)

Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial (HOPE) (Michigan, New Mexico)

Home Transcutaneous Electrical Acustimulation (TEA) (Home-TEA) (Michigan)

Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain (GRACE) (Florida, Illinois, North Carolina)

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment (IMPOWR-MORE) (New Jersey, Utah)

IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs (New York)

Latinx Children and Surgery (California)

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome (Massachusetts)

Nonpharmacologic Pain Management in FQHC Primary Care Clinics (BeatPain Utah) (Utah)

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain (KALPAS) (Alabama, Arkansas, Illinois, Massachusetts, Minnesota, Missouri, New York, Pennsylvania, Texas, Washington)

Pain and Opioids: Integrated Treatment In Veterans (POSITIVE) (California, Washington, New Mexico)

Pain Care at Home to Amplify Function (Pain CHAMP) (Arkansas, Colorado, Connecticut)

PAINED: Project Addressing INequities in the Emergency Department (PAINED) (Washington, D.C.)

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP) (Maryland, Oregon, Pennsylvania, West Virginia)

Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment (New York)

Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization (Micro-bupe) (New York)

Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UG3 Pilot (RAMP UG3) (Minneapolis)

Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI) (North Carolina)

Stepped Care for Patients to Optimize Whole Recovery (SC-POWR) (Connecticut)

The Back Pain Consortium Research Program Study (BACPAC) (Michigan)

Treating Negative Affect in Low Back Pain Patients (TNA-LBP) (Massachusetts, Minnesota, Pennsylvania)