NIH HEAL Initiative 2023 Annual Report

Now in its fourth year of funding, the NIH Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, continues to seek urgent answers to the nation’s evolving pain and opioid crises. This past year saw some noteworthy accomplishments with direct implications for policy and practice:

  • Defining a new standard of care for soothing infants born with neonatal opioid withdrawal syndrome
  • Delivery of nearly 1,000 evidence-based interventions into U.S. communities hit hard by the crisis
  • Reduced re-arrest among incarcerated individuals who received opioid treatment in jail
  • Advanced cutting-edge technologies for identifying new pain therapeutics

As you’ll see in this year’s report, HEAL continues to build and grow essential partnerships with patients and communities, federal and state agencies, and professional organizations committed to advancing health options for people with poorly treated pain, opioid use disorder, and mental illness.

Read the full report. pdf  745.53 KB*

*Please note this report is being remediated for Section 508 compliance. We will post a compliant PDF soon.

Previous Annual Reports


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Open Funding Opportunities

The NIH HEAL Initiative® funds work in research focus areas led by most NIH ICs supporting hundreds of projects, from basic science to implementation research.

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About NIH HEAL Initiative®

The Helping to End Addiction Long-term Initiative, or NIH HEAL Initiative® , is an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis.

Learn About HEAL

Research Programs

Research from the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®, includes over 31 distinct programs. These programs are led by most NIH Institutes, Centers, and Offices. 

View Research Programs