Funded Projects

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Project #	Project Title	Research Focus Area	Research Program	Administering IC Sort descending	Institution(s)	Investigator(s)	Location(s)	Year Awarded
3-UH3-AT010739-02 Show Summary	Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults	Clinical Research in Pain Management	Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM)	NCCIH	KAISER FOUNDATION RESEARCH INSTITUTE	SHERMAN, KAREN J (contact); DEBAR, LYNN L	Oakland, CA	2021
NOFO Title: HEAL Initiative: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements to Support Strategies to Increase Participant Diversity, Inclusion and Engagement in Clinical Studies NOFO Number: NOT-NS-21-025
3R61AT010604-01S1 Show Summary	Behavioral Economics based stigma reduction intervention for low income, African American individuals with OUD	Translation of Research to Practice for the Treatment of Opioid Addiction	Behavioral Research to Improve Medication-Based Treatment	NCCIH	UNIVERSITY OF TENNESSEE HEALTH SCI CTR	DEREFINKO, KAREN J	Memphis, TN	2020
NOFO Title: HEAL Initiative: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements to Support Strategies to Reduce Stigma in Pain Management and Opioid Use Disorder (OUD) and Treatment NOFO Number: NOT-OD-20-101 Summary: Buprenorphine-naloxone is known to work for the treatment of Opioid Use Disorder (OUD). However, despite its success in treating OUD, retention for these kinds of medication-assisted treatments (MATs) for OUD is notoriously low, having a dropout rate of approximately 50 percent within the first 6 months. One factor known to negatively impact a person?s adherence to treatment is stigma. This includes, not only stigma associated with having OUD, but also that of multiple stigmatized identities, including stigma associated with race. The goal of this supplement award is to decrease OUD- and race-related stigma in low income African American communities using a Behavioral Economics Stigma Reduction intervention that functions at the intrapersonal, interpersonal, and community levels. The investigators will work at the individual level to address stigma in untreated individuals who present with OUD at local community or faith organizations through stigma reduction counseling and tangible rewards for treatment uptake. To assess the interpersonal stigma, referred family members or support persons of these individuals will also be enrolled to receive stigma reduction and supportive skills counseling. Finally, a stigma reduction campaign will be developed and administered to the community via social media and billboards. Community members? substance use stigma will be compared before and after the campaign.
4R33AT010106-02 Show Summary	Psychosocial pain management to improve opioid use disorder treatment outcomes	Translation of Research to Practice for the Treatment of Opioid Addiction	Behavioral Research to Improve Medication-Based Treatment	NCCIH	University of Michigan at Ann Arbor	ILGEN, MARK	Ann Arbor, MI	2019
NOFO Title: Clinical Trials or Observational Studies of Behavioral Interventions for Prevention of Opioid Use Disorder or Adjunct to Medication Assisted Treatment-SAMHSA Opioid STR Grants (R21/R33) NOFO Number: RFA-AT-18-002
1R01AT010742-01 Show Summary	Mindful Body Awareness Training as an Adjunct to Medication Assisted Treatment for Opioid Use Disorder: An ancillary study	Translation of Research to Practice for the Treatment of Opioid Addiction	Behavioral Research to Improve Medication-Based Treatment	NCCIH	University of Washington	PRICE, CYNTHIA J (contact); MERRILL, JOSEPH O	Seattle, WA	2019
NOFO Title: HEAL Initiative Limited Competition: Behavioral Research to Improve MAT: Ancillary Studies to Enhance Behavioral or Social Interventions to Improve Adherence to Medication Assisted Treatment for Opioid Use Disorders (R01 Clinical Trial Optional) NOFO Number: RFA-AT-19-007 Summary: Opioid use disorder interventions need to address the complex needs of patients, which include substantial mental health comorbidity and high rates of chronic pain. This study takes advantage of recent federal and state opioid use disorder treatment initiatives as a platform for testing a promising mind-body intervention, Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to Medication Assisted Treatment (MAT) with buprenorphine in clinical settings funded through the Washington Opioid State Targeted Response (STR) program. Using a randomized, repeated measures design, the study team will compare those who receive MABT+ MAT to MAT only. The overarching goal of this application is to test MABT to improve MAT outcomes among patients receiving buprenorphine to treat OUD. Results of this study will inform the evidence base for behavioral treatment adjuncts to MAT with buprenorphine and directly impact the future direction of opioid use disorder treatment in Washington state.
3R61AT010799-01S2 Show Summary	Understanding How Peers Can Shift Stigma to Retain Low-Income, Minority Individuals in Opioid Treatment	Translation of Research to Practice for the Treatment of Opioid Addiction	Behavioral Research to Improve Medication-Based Treatment	NCCIH	UNIV OF MARYLAND, COLLEGE PARK	MAGIDSON, JESSICA F	College Park, MD	2020
NOFO Title: HEAL Initiative: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements to Support Strategies to Reduce Stigma in Pain Management and Opioid Use Disorder (OUD) and Treatment NOFO Number: NOT-OD-20-101 Summary: Stigma is a key barrier to retention in medication-based treatment for opioid use disorder, particularly among low-income, minority individuals. Stigma that exists at multiple levels contributes to poor retention in care, including internalized and anticipated stigma at the individual level, as well as enacted stigma at the health care provider- and community levels. There is an urgent need to develop and evaluate innovative strategies to reduce stigma at these multiple levels among low-income, racial/ethnic minority individuals to improve engagement in care. One of the most promising strategies to reduce multiple intersecting stigmas simultaneously and improve engagement in care for low-income, minority individuals is through the use of peer recovery coaches (PRCs). PRCs, individuals who have gone through the recovery process themselves and are typically state-certified, have been shown to be more acceptable for engaging and retaining low-income, racial/ethnic minority patients in treatment compared to other health workers. However, scarce research has formally evaluated the effects of PRCs on stigma. This study will test how a PRC model can reduce multiple intersecting stigmas among low-income, racial/ethnic minority individuals to improve retention in methadone treatment.