Funded Projects

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Project # Sort descending	Project Title	Research Focus Area	Research Program	Administering IC	Institution(s)	Investigator(s)	Location(s)	Year Awarded
1U24AT010961-01	HEAL Collaboratory Resource Coordinating Center (PRISM)	Clinical Research in Pain Management	Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM)	NCCIH	DUKE UNIVERSITY	HERNANDEZ, ADRIAN (contact); CURTIS, LESLEY H; WEINFURT, KEVIN P	Durham, NC	2019
NOFO Title: HEAL Initiative: Limited Competition: Resource Coordinating Center for Pragmatic and Implementation Studies for the Management of Pain (PRISM) to Reduce Opioid Prescribing (U24 Clinical Trial Not Allowed) NOFO Number: RFA-AT-19-011 Summary: Improved pain management and reduction of opioid use could greatly benefit from improved pragmatic clinical trials (PCTs). The PRISM Resource Coordinating Center (CC), as part of the NIH Health Care Systems Research Collaboratory, will support up to nine more embedded PCTs that address pain management and the opioid crisis. Since 2012, the CC has nurtured 15 Demonstration Projects by providing leadership, resources, tools, training, and coordination of diverse elements. The CC will work collaboratively with each PRISM Demonstration Project team supported through the HEAL Initiative, including their partnering health care systems, to develop, test, and implement the projects while providing technical, design, and coordination support. The CC will also develop and refine technical and policy guidelines and best practices for the effective conduct of pain-related research studies in partnership with health care systems and disseminate best strategies for successful embedded PCTs.
1U24DA050182-01	Coordinating Center to Support NIDA Preventing Opioid Use Disorder in Older Adolescents and Young Adults	New Strategies to Prevent and Treat Opioid Addiction	Preventing Opioid Use Disorder	NIDA	RTI Institute	Graham, Phillip W. (contact); Ridenour, Ty A.	Research Triangle Park, NC	2019
NOFO Title: HEAL Initiative: Coordinating Center to Support NIDA Preventing Opioid Use Disorder in Older Adolescents and Young Adults (ages 16–30) Initiative (U24 Clinical Trial Not Allowed) NOFO Number: RFA-DA-19-034 Summary: The Coordinating Center (CC) will provide centralized logistical support and facilitate communication and coordination of activities across the cooperative. The CC will provide scientific leadership, which will include providing scientific expertise in the areas of implementation research and economic evaluation. The CC will establish an infrastructure for cross-site data collection, management, harmonization, and data sharing and provide expert methodological and statistical consultation.
1U24DA055325-01	The Healthy Brain and Child Development National Consortium Administrative Core	Enhanced Outcomes for Infants and Children Exposed to Opioids	HEALthy Brain and Child Development Study (HBCD)	NIDA	UNIVERSITY OF CALIFORNIA, SAN DIEGO	CHAMBERS, CHRISTINA (contact); NELSON, CHARLES ALEXANDER	La Jolla, CA	2021
NOFO Title: HEAL Initiative: HEALthy Brain and Child Development Consortium Administrative Core (U24 - Clinical Trial Not Allowed) NOFO Number: RFA-DA-21-022 Summary: The HEALthy Brain and Child Development National Consortium (HBCD-NC) Administrative Core (HCAC) will coordinate efforts across all sites in the HBCD-NC consortium to ensure that the consortium meets its primary objective to establish a normative model of developmental trajectories over the first 10 years of life. The HBCD-NC will collect neural, behavioral, physiological, and psychological measures, as well as biospecimens, to characterize neurodevelopmental trajectories. The HCAC will oversee study design and monitor the progress of each site’s ability to carry out a common research protocol and will assemble and distribute a comprehensive research dataset to the scientific community. This administrative core is located at the University of California, San Diego.
1U24DA055330-01	Healthy Brain and Child Development National Consortium Data Coordinating Center	Enhanced Outcomes for Infants and Children Exposed to Opioids	HEALthy Brain and Child Development Study (HBCD)	NIDA	WASHINGTON UNIVERSITY	SMYSER, CHRISTOPHER DANIEL (contact); DALE, ANDERS M; FAIR, DAMIEN A	St Louis, MO	2021
NOFO Title: HEAL Initiative: HEALthy Brain and Child Development Data Coordinating Center (U24) NOFO Number: RFA-DA-21-023 Summary: The HEALthy Brain and Child Development National Consortium (HBCD-NC) Data Coordinating Center (HDCC) will provide data management and oversight to all HBCD-NC sites to ensure the consortium’s primary objective of establishing a normative template of developmental trajectories over the first 10 years of life is met. The HBCD-NC will collect neural, behavioral, physiological, and psychological measures, as well as biospecimens, to characterize neurodevelopmental trajectories. The HDCC will coordinate data collection, data quality, data harmonization, data sharing, and data analysis efforts that are central to the consortium’s ability to implement a common research protocol. The HDCC will assemble all data across the consortium sites and distribute a comprehensive and well curated research dataset to the scientific community at large. The HDCC is tightly integrated with the HEALthy Brain and Child Development Administrative Core (HCAC) and includes a multi-institution investigative team at the University of Minnesota, University of California, San Diego, and Washington University at St Louis.
1U24DA057612-01	WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use Disorder	Cross-Cutting Research	Translating Data 2 Action to Prevent Overdose	NIDA	WAKE FOREST UNIVERSITY HEALTH SCIENCES	ADAMS, MEREDITH C B	Winston-Salem, NC	2022
NOFO Title: HEAL Initiative: HEAL Data2Action Data Infrastructure Support Center (U24 Clinical Trial Optional) NOFO Number: RFA-DA-22-052 Summary: This project creates the HEAL Data2Action Data Infrastructure Support Center that will conduct research as well as support the HEAL Data2Action Innovation Projects with analytics and support for navigating electronic health records and other “big data” sources, as well as logistical processes related to privacy and ethics. The center will help plan for data collection and assessing outcomes, as well as provide data visualization efforts for various stakeholders. Key support mechanisms include courses, seminars, conferences, trainings, and on-demand technical assistance.