Funded Projects

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Project #	Project Title	Research Focus Area	Research Program	Administering IC	Institution(s)	Investigator(s)	Location(s) Sort descending	Year Awarded
1U24DA057612-01 Show Summary	WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use Disorder	Cross-Cutting Research	Translating Data 2 Action to Prevent Overdose	NIDA	WAKE FOREST UNIVERSITY HEALTH SCIENCES	ADAMS, MEREDITH C B	Winston-Salem, NC	2022
NOFO Title: HEAL Initiative: HEAL Data2Action Data Infrastructure Support Center (U24 Clinical Trial Optional) NOFO Number: RFA-DA-22-052 Summary: This project creates the HEAL Data2Action Data Infrastructure Support Center that will conduct research as well as support the HEAL Data2Action Innovation Projects with analytics and support for navigating electronic health records and other “big data” sources, as well as logistical processes related to privacy and ethics. The center will help plan for data collection and assessing outcomes, as well as provide data visualization efforts for various stakeholders. Key support mechanisms include courses, seminars, conferences, trainings, and on-demand technical assistance.
1R43DA058614-01 Show Summary	Combination Therapeutic for Chronic Opioid Use Disorder Relapse	Cross-Cutting Research	Small Business Programs	NIDA	APHIOS CORPORATION	CASTOR, TREVOR P	Woburn, MA	2023
NOFO Title: PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) NOFO Number: PA-22-176 Summary: Side effects from taking the opioid receptor blocker naltrexone make it difficult for patients to adhere to treatment with this medication for opioid use disorder. Cannabidiol (CBD), a bioactive ingredient of cannabis, is not an opioid and is non-psychoactive. Previous research shows that CBD blocks opioid-seeking behaviors, craving, and withdrawal. This project will develop tiny particles containing CBD and low-dose naltrexone. The research will determine if this combined version of CBD and naltrexone helps people stay in treatment and prevents relapse without problematic side effects.
3R01MH128904-02S1 Show Summary	Supporting Treatment Access and Recovery for Co-Occurring Opioid Use and Mental Health Disorders (STAR-COD)	Cross-Cutting Research	Increasing Participant Diversity, Inclusion, and Engagement in HEAL Research	NIMH	UNIV OF MASSACHUSETTS MED SCH WORCESTER	SMELSON, DAVID A (contact); GONZALEZ, GERARDO ; LI, WENJUN ; OLMSTEAD, TODD ALDEN	Worcester, MA	2022
NOFO Title: HEAL Initiative: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements to Support Strategies to Increase Participant Diversity, Inclusion and Engagement in Clinical Studies NOFO Number: NOT-NS-22-066 Summary: Black/African American and Hispanic/Latino individuals suffer a disproportionate burden of co-occurring substance use and mental illness, in part due to reduced access to culturally responsive quality healthcare, compared to other racial/ethnic groups. In addition, Black/African American and Hispanic/Latino individuals are not well represented in clinical trials that could help reduce these health disparities. This research aims to improve the recruitment of Black/African American and Hispanic/Latino individuals to participate in clinical research related to co-occurring substance use and mental illness. The project will conduct community engagement and community-based participatory research, establishing a bidirectional partnership between researchers and community members.