Third Annual NIH HEAL Initiative Investigator Meeting

Mon, 4/11/2022 - 10:00am
Tue, 4/12/2022 - 4:30pm

Past event. This event already took place. Visit this webpage for upcoming events.


The NIH HEAL Initiative® convened the third annual meeting of more than 400 NIH HEAL Initiative awardees, federal officials, people with lived experience, and other stakeholders to share research findings, explore trends and shared interests, and identify opportunities to advance the goals of the initiative.

This meeting brought together researchers from around the country who are taking on the pain and opioid crises from all angles. These researchers study a broad range of topics, such as innovative technology-based therapies for pain management; community-based integrated solutions for prevention, overdose, and medication-based treatment for opioid use disorder; and a variety of new approaches for managing pain.

Topics Covered

  • The evolution of the opioid crisis.
  • Inclusion of communities and people with lived experience in all stages of research.
  • The intersection of pain and opioid use disorder.
  • Development of novel and personalized treatment approaches.
  • The translation of research to practice, including prevention.
  • Ways to facilitate data sharing and opportunities for new discovery through collaboration.
  • Addressing the opioid crisis from many angles with federal partners.

Key Takeaways

  • The pain and opioid use disorder research communities must work together to address shared risk factors and experiences, identify common intervention targets, and integrate treatment.
  • To enhance study recruitment as well as treatment accessibility and acceptance, community engagement is essential, as is building trust between researchers and the community using targeted approaches.
  • More efforts are necessary to reduce stigma associated with pain, opioid use disorder, and medications for opioid use disorder at multiple levels, especially among healthcare providers.
  • HEAL research needs to address changing substance use patterns, including polysubstance use and increased presence of fentanyl in other drugs, as well as changes in populations at risk.
  • Better data collection and enhanced data sharing are essential to promote new knowledge and inform responses to the pain and opioid crises.
  • Multi-tiered approaches are necessary to address all aspects of the opioid crisis, including improved pain management, prevention of opioid use disorder and overdose, treatment of opioid use disorder and overdose, recovery support, and disruption of drug supplies.

View the Meeting Summary pdf  450.29 KB.

Day 1 (Monday, April 11, 2022)

10:00 – 10:30 a.m.
Welcome and Introduction
Dr. Rebecca Baker, Director, Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®
Dr. Lawrence Tabak, Acting Director, National Institutes of Health (NIH)

Keynote Address: What Are We Doing, and What Can We Do Better, to End the Overdose Epidemic?
Admiral Rachel L. Levine, M.D., Assistant Secretary for Health, U.S. Department of Health and Human Services

10:30 – 10:45 a.m.
Helping to End Addiction Long-term Initiative: Progress and Priorities pdf  1.61 MB*
Dr. Rebecca Baker, Director, NIH HEAL Initiative

10:45 – 11:25 a.m.
Dialogue: NINDS and NICHD Directors in Conversation With the HEAL Community Partner Committee
NIH Facilitator: Dr. Rebecca Baker, Director, NIH HEAL Initiative

NIH Discussants: Dr. Walter Koroshetz, Director, National Institute of Neurological Disorders and Stroke (NINDS)
Dr. Diana Bianchi, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

HEAL Community Partner Committee (HCPC) Discussants:
Kevin Charles, Family and Medical Counseling, Inc.
Jessica Hulsey Nickel, Addiction Policy Forum
Bianca Prieto, Georgia Council on Substance Abuse
Philip Rutherford, Faces & Voices of Recovery
Stephanie Smith, Former HEAL Knee Osteoarthritis Study Participant
Christin Veasley, Chronic Pain Research Alliance

11:35 a.m. – 12:30 p.m.

Plenary: At the Intersection of Pain and Opioid Use Disorder—Bringing the Research Communities Together
NIH Facilitators: Dr. Walter Koroshetz, Director, NINDS; and Dr. Nora Volkow, Director, National Institute on Drug Abuse (NIDA)
HEAL Investigator Facilitator:
Assessing and Addressing the Clinical Needs of Patients with Chronic Pain and Opioid Use Disorder pdf  138.95 KB*
Dr. Declan Barry, Yale School of Medicine

Integrated Approach to Pain and Opioid Use in Hemodialysis Patients pdf  1.69 MB*
Dr. Manisha Jhamb, University of Pittsburgh
Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) pdf  7.96 MB*
Dr. Katie Witkiewitz, University of New Mexico

12:30 – 1:10 p.m.
Fireside Chat: Addressing the Overdose Epidemic From Many Angles
Dr. Rahul Gupta, Director, White House Office of National Drug Control Policy and Dr. Lawrence Tabak, Acting Director, NIH

2:00 – 3:00 p.m. (CLOSED TO PUBLIC)
Discussion Groups

3:00 – 4:00 p.m. (CLOSED TO PUBLIC)
Poster Session and Networking

4:00 – 5:00 p.m.
Scientific Symposium: Advancing Research to Practice
NIH Facilitator: Dr. Helene Langevin, Director, National Center for Complementary and Integrative Health
HEAL Investigator Facilitator: Dr. Donald Penzien, Wake Forest School of Medicine

Recidivism and mortality after in-jail buprenorphine treatment for opioid use disorder pdf  1.77 MB*
Dr. Elizabeth Evans, University of Massachusetts Amherst
HCS Community Health Campaigns – Shifting from Engagement to Action pdf  13.09 MB*
Dr. Craig Lefebvre, RTI International
NOHARM: Non-pharmacological Options in post-operative Hospital-based And Rehabilitation pain Management pragmatic trial pdf  4.53 MB*
Dr. Andrea Cheville, Mayo Clinic Rochester
JCOIN PIERS: Providing Interventions for Enhancing Recovery during Supervision pdf  3.47 MB*
Rising Star: Dr. Lauren Brinkley-Rubinstein, University of North Carolina at Chapel Hill

5:00 – 5:45 p.m.
NIDA Director, Dr. Nora Volkow in Conversation With Maia Szalavitz, Journalist and Author of Undoing Drugs: The Untold Story of Harm Reduction and the Future of Addiction, and the New York Times Bestseller, Unbroken Brain.

5:45 p.m.

Day 2 (Tuesday, April 12, 2022)

10:00 – 10:10 a.m.
Dr. Rebecca Baker, Director, NIH HEAL Initiative®

The Opioid Crisis: Scientific Challenges and Opportunities

Dr. Nora Volkow, Director, NIDA

10:10 – 11:10 a.m.
Scientific Symposium: Advancing the Pain and Addiction Therapeutic Research Pipeline
NIH Facilitator: Dr. Joni Rutter, Director, National Center for Advancing Translational Sciences
HEAL Investigator Facilitator: Dr. Sandra Comer, Columbia University

REINVENT MEDICINE FOR A HEALTHIER WORLD: Weekly Oral Levomethadone pdf  6.01 MB*
Dr. Richard Scranton, Lyndra Therapeutics
FKBP51 as a promising therapeutic target for the prevention of chronic posttraumatic pain pdf  1.62 MB*
Dr. Sarah Linnstaedt, University of North Carolina at Chapel Hill
Multi-organ-on-chip Device for Modeling Opioid Reinforcement and Withdrawal, and the Negative Affective Component of Pain: a Therapeutic Screening Tool pdf  1.03 MB*
Dr. Stephanie Seidlits, University of California, Los Angeles
Rising Star: Dr. Amol Patwardhan, University of Arizona

11:10 a.m. – 12:10 p.m.
Plenary: Better Together—Collective HEALing Through Data Sharing pdf  420.59 KB*
NIH Facilitator: Dr. Jessica Mazerik, NIH HEAL Initiative
RENCI Facilitator: Dr. Kira Bradford, Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill

The case for collaborative, large scale studies and aggressive data sharing policies:  The ABCD Study Data Sharing Model pdf  4.23 MB*
Dr. Terry Jernigan, University of California San Diego
Data Harmonization of HEAL Prevention Outcomes Studies pdf  2.19 MB*
Dr. Ty Ridenour, RTI International, University of North Carolina at Chapel Hill
HEAL Pain Common Data Elements (CDE) Program pdf  2.67 MB*
Dr. Laura Wandner, NINDS
HEAL Data Platform pdf  2.19 MB*
Dr. Robert Grossman and Dr. Phil Schumm, University of Chicago
HEAL Study-level Core Metadata pdf  642.11 KB*
Dr. Andrea Tentner, University of Chicago

1:10 – 2:10 p.m. (CLOSED TO PUBLIC)
Discussion Groups

2:10 – 3:10 p.m. (CLOSED TO PUBLIC)
Poster Session and Networking

3:10 – 4:00 p.m.
Federal Panel: How Can Science Inform the Federal Response to the Opioid Crisis?
NIH Facilitator: Dr. Lawrence Tabak, Acting Director, NIH

Dr. Robert Califf, Commissioner, U.S. Food and Drug Administration
Dr. Debra Houry, Acting Principal Deputy Director, Centers for Disease Control and Prevention
Dr. Miriam Delphin-Rittmon, Assistant Secretary for Mental Health and Substance Use, Substance Abuse and Mental Health Services Administration

4:00 – 4:30 p.m.
Observations and Future Directions for HEAL pdf  2.51 MB*
Dr. Rebecca Baker, Director, NIH HEAL Initiative and Dr. Lawrence Tabak, Acting Director, NIH

4:30 p.m.

*These slides are in the process of being made Section 508-compliant.

Videos From the Event

Video recordings of the open sessions of this meeting are available. Please refer to the “View Full Agenda with Presentations” section for session details.

Monday, April 11

Morning Session (10:00 a.m. – 1:10 p.m.):

Afternoon Session (4:00 – 5:45 p.m.):


Tuesday, April 12

Morning Session (10:00 a.m. – 12:10 p.m.):

Afternoon Session (3:10 – 4:30 p.m.):

Third Annual Investigator Meeting Director’s Message

Dr. Baker provides an overview about the Third Annual Investigator Meeting.

Read More

2021 HEAL Initiative Investigator Meeting

This meeting brought together researchers from around the country that are taking on the pain and opioid crises from all angles.

Read More

Research Programs

Research from the NIH HEAL Initiative® includes more than 30 distinct programs. These programs are led by most NIH Institutes, Centers, and Offices.

Learn More