Optimizing Collaborative Care for People with Opioid Use Disorder and Mental Health Conditions

Overview

The Research Need

There is an urgent need to identify effective approaches to treat people who have an opioid use disorder (OUD) and co-occurring mental health conditions, especially in primary care settings. Data from the 2016 National Survey on Drug Use and Health suggest that among adults who misused opioids in the prior year, 42.8 percent also had a mental illness and 15.6 percent had a serious mental illness.

The collaborative care model is a promising approach to meeting the needs of people who have both OUD and mental health conditions. Collaborative care is a specific service delivery model for treating mental and behavioral conditions in primary care settings.

Strong evidence supports collaborative care for treating people with common mental disorders, including those who have physical health conditions. Researchers have demonstrated that collaborative care improves clinical outcomes and is associated with improvements in access to care (getting people care who need it), continuity of care (keeping people in care who might otherwise fall through the cracks), and health equity.

Promising but less definitive evidence is available about the effectiveness of collaborative care for treating OUD and other substance use disorders. And less definitive information exists about how best to implement the model in primary care settings for people with both OUD and mental health conditions. Research is needed to help fill gaps about the effectiveness of collaborative care for treating OUD and other substance use disorders and implementing the model in primary care settings for people with both OUD and mental health conditions.

About the Program

This program will support research to develop, optimize, and test the collaborative care model using medication for OUD and evidence-based treatments for mental health conditions that can be delivered within primary care settings.

Researchers will focus on leveraging strong research-practice partnerships and on harnessing the expertise of interdisciplinary teams for the diagnosis and treatment of OUD and mental health disorders. They will develop screening methods to identify people who have OUD and co-occurring mental health disorders and assess the cost, effectiveness, and sustainability of collaborative care strategies. Researchers will also evaluate multiple methods of collaborative care in rural and urban settings and in areas with a shortage of health professionals.

Program Details

To date, through the Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, NIH has awarded four research grants totaling approximately $50 million. Each awardee will carry out clinical trials to test not only whether collaborative care improves clinical outcomes but also whether it improves outcomes related to access to care and continuity of care. Each awardee will also conduct economic analyses to investigate how to make their collaborative care models financially feasible in clinical practices once the research concludes.

Research Examples

These projects will:

  • Use pragmatic designs and deployment-focused interventions that are feasible to implement in existing clinical practice settings.
  • Be conducted in high need locations.
  • Serve diverse patient populations, including racial and ethnic minorities, pregnant women, and participants younger than 18.
  • Take place in clinics with known variation in implementation readiness and existing site resources.
  • Aim to answer research questions about cost and cost-effectiveness and about the reduction of the alarming rates of mortality associated with OUD.
  • Seek to streamline workflows through routine screening and efficient referral pathways to medication-based treatment for OUD and mental health treatment.

  • Kaiser Foundation Research Institute – California
  • Rand Corporation – California
  • University of Pennsylvania – Pennsylvania
  • University of Washington – Washington

Funded Projects

2019
Collaborating to Heal Addiction and Mental Health in Primary care (CHAMP)
Sep 25, 2019
2019
Improving Access and Treatment for Co-occurring Opioid Use Disorders and Mental Illness
Sep 25, 2019
2019
Patient-centered team-based primary care to Treat Opioid Use Disorder, Depression, and Other conditions
Sep 25, 2019
2019
The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions
Sep 25, 2019