Researchers are looking for ways to predict which individuals with pain can recover on their own and which don’t

HEAL SPRINT study aims to identify culprit factors that predict chronic pain in teens

New HEAL research program expands innovation

Combinations of animal and human studies explore sleep and circadian rhythms to target opioid use.

A molecular inventory of pain-sensing nerve cells may lead to more targeted therapies

Human cell model mimics breathing center shut down by overdose

Finding the Best Treatment for Individual Patients

Access to real-time data helps treatment providers and harm reduction organizations

Connecting Pain Scientists Through the PURPOSE Network

The Power of the HEAL Data Ecosystem

Exploring family support as a way to protect and manage chronic pain for older African Americans.

The Restoring Joint Health and Function to Reduce Pain (RE-JOIN) Consortium

HEAL-funded researchers work together with D.C. communities hard-hit by the opioid crisis

Treating the brain with non-invasive stimulation

Can a single dose of ketamine prevent chronic pain and depression after mastectomy?

HEAL researchers are creating new tools in the toolbox in the quest to help patients with back pain. Learn about "microgels."

Examining the Role of Pain Coping Skills

Dr. Allan Basbaum explains why interacting with pain patients is important for basic scientists.

Can resetting brain circuits help people find recovery?

Seeking sustainable models of integrated care

Successful approaches to research partnerships with patients and communities

HEAL prevention research targets systems for sustainability

Targeting the causes of opioid misuse and addiction

Questions and answers with Amy Goldstein and Barbara Oudekerk

Helping people in jails get treatment

Better Sleep Eases Opioid Withdrawal and Cuts Drug Craving

“Artificial muscle” may help prevent back problems

Long-acting methadone could make treatment easier

Understanding how environmental exposures affect infant and child brain development

An implanted device that detects an overdose and administers naloxone

Innovative research for people with chronic pain and risky opioid use or opioid use disorder

New treatment options on the horizon for pain associated with sickle cell disease

Tissue chip-based model screens potential pain medications faster

New personalized text-messaging app may make it easier for people with opioid use disorder to continue buprenorphine treatment

HEAL-funded researchers are investigating the role of sleep deficiency in opioid use disorder and relapse risk

Research strategy targets craving to treat addiction

HEAL-funded researchers develop tools for primary care providers to identify and help patients at risk of suicide

NIH HEAL Initiative research aims to help people stay in recovery long-term

Introducing early career investigators involved in the NIH HEAL Initiative

Connecting people with opioid use disorder with treatment

Everyone wins when we dismantle stigma

HEAL researchers combine antidepressants and physical therapy

HEAL-funded researchers develop an MRI-compatible crib

Turning tarantula venom into a non-opioid treatment for pain

HEAL-funded research team is using the power of play to prevent opioid misuse in youth

Helping vulnerable populations acquire treatment for low back pain

Using bone glue to treat pain from wisdom-tooth extractions

Toward personalized care for people treated with dialysis

NIH HEAL research aims to address stigma among healthcare providers

Questions and answers with the HEAL Patient Engagement Working Group

Can immersive experiences provide relief by distracting patients from pain?

Re-envisioning how the criminal justice system responds to the opioid crisis

Communities and scientists join forces to save lives from opioid use disorder

Community members are working to save lives from opioid-related overdoses

A small company is developing a new way to create a safe extended-release pain medication

A team of scientists at Knopp Biosciences LLC, is innovating treatments to manage neuropathic pain by aiming at its source — hyperactive nerve cells.

An NIH HEAL Initiative® research team is searching for new targets for non-addictive pain treatments

The NIH HEAL Initiative wants to learn from examples of successful strategies used by researchers that meet patients where they are and invite them to join the research process. Email [email protected]

From surgery and drugs to cell-based therapies, researchers will test innovative, non-addictive approaches for treating pain.

The NIH HEAL Initiative supports research that looks at the relationship of prenatal exposure of opioids on brain function in infants. Research also studies the role that prenatal exposure to opioids might play in the emergence of congnitive and behavioral issues.

Project aims to improve pain relief while supporting treatment for opioid use disorder and long-term recovery.

Studies in animals test the effects of sleep deficiency in opioid misuse and addiction.

Testing medication-based treatment for opioid use disorder for the long-term.

Support system model encourages young adults to access and continue medication-based treatment to achieve long-term recovery.

With new technology, researchers can understand the effects of repeated overdoses and test new treatments.

NIH HEAL Initiative research seeks better long-term outcomes for babies with neonatal opioid withdrawal syndrome, or NOWS.

Researchers develop a new type of injectable electrode for neuromodulation therapy.

Scientists identified a group of neurons in mice that blunt pain within the brain. Such neurons could be promising targets for new non-addictive therapies for chronic pain.

A computer model may be able to inspire new insights and treatments.

Can a team-based approach improve treatment for people with both opioid use disorder and mental health conditions?

Research explores the integration of medication-based treatment with the healing traditions of American Indian and Alaska Native communities.

NIH HEAL Initiative study aims to improve outcomes for mothers after cesarean deliveries.

An NIH HEAL Initiative project is studying whether a telemedicine system to connect women with treatment providers and peer support before their release from jail can help the women stay in treatment and recover from opioid use disorder once in the community.

Research funded by the NIH HEAL Initiative® is studying whether a web-based program can help people cope with chronic pain.

An NIH HEAL Initiative® study is using a computer simulation program with virtual patients to help real doctors understand their biases when assessing their patients’ risk of opioid misuse.

The NIH HEAL Initiative® — an aggressive research effort led by the National Institutes of Health (NIH) — aims to prevent opioid overdose deaths and improve how we understand and treat both pain and opioid addiction.

Doctors can’t predict how much pain a person will feel after surgery, making tailored treatments difficult. One NIH HEAL Initiative researcher hopes to develop a blood test to predict how sensitive people will be to pain.

The NIH HEAL Initiative® is funding a project to develop a long-lasting implant to release medication for opioid use disorder to help patients stay on treatment and achieve long-term recovery.

HEAL challenged researchers to consider stigma when planning ways to address the opioid crisis.